Protein function prediction based on genome sequence

Yura, Kei

Puroteomikusu No Saishin Gijutsu, p.93 - 101, 2002/11

Determination of genome sequences has massive impacts on biology. Genome sequence is a blueprint of the species, and analyses of genome sequence may uncover every components of the species. However, when a whole genome of Haemophilus influenzae was sequenced, biologists realized that one was not able to deduce biological information out of the sequence. The genome sequence is full of information that knowledge based on conventional genetics and molecular biology can retrieve. Bioinformatics is the field that find niche in this area. In this chapter, we will overview the current status and the future of bioinformatics.